Myghty is a Python-based Web application framework originally ported from HTML::Mason. It supports the full feature set of Mason, allowing component-based Web development with Python-embedded HTML.
TurboGears is a Python web development framework that packages other frameworks:
Web
Ajax
Programming
python
web-framework
TurboGears
License:MIT
“The Web Framework for Perfectionists with Deadlines.”
Django is a high-level Python Web framework that encourages rapid development and clean, pragmatic design.
Initially developed at a local newspaper in Kansas, it has since found favour for developing all kinds of sites and applications, from content-heavy sites such as www.lawrence.com to Web 2.0 applications such as www.tabblo.com.
Django is quite popular for its extensive documentation.